Integrated research on Developmental determinants of Ageing and Longevity

IDEAL Training

Weighted Network Analysis at Leiden University Medical Center

Date: 12th - 13th of May 2014, Venue: LUMC, Albinusdreef 2, 2333 ZA Leiden, Building 1, Room: J1-83 Leiden, The Netherlands

URL for registration:https://sites.google.com/site/networkslumc2014/weighted-network-analysis

Instructor: Prof Steve Horvath, Department of Biostatistics, UCLA School of Public Health

This two-day intensive course will cover (weighted) network analysis methods widely used in systems biologic and systems genetic applications. The goal of the network analysis workshop is to familiarize researchers with network methods and software for integrating genomic data sets with complex phenotype data. Participants will learn how to integrate disparate data sets (genetic variation, gene expression, protein interaction networks, complex phenotypes, gene ontology information, DNA methylation) and use networks for identifying disease genes, pathways and key regulators.


This workshop is organized by the MIMOmics consortium.logo mimomics lr web

 

Course "Epigenesis and Epigenetics" at Wageningen University

Date: 21st - 23rd of May 2014, Venue: Conference centre ‘Hof van Wageningen’, Wageningen, The Netherlands

URL:http://www.vlaggraduateschool.nl/courses/epi-gen.htm

Nutritional conditions in early life may, through epigenetic and epigenesist processes, have profound effects on  physiological functioning and health in later life. This course aims to provide a detailed scientific background on the mechanisms that may underlie these early-life effects, both at the physiological and gene expression level. The program combines knowledge on perinatal programming by nutritional factors  in humans, laboratory and farm animals.

The course is aimed at postgraduates (MSc, PhD) with a background in animal, veterinary, biological, health, or food sciences and open for participants from both industry and universities/research centers. Participants are challenged to actively contribute to discussions, within the programme two sessions are devoted to this (6 short oral presentations on day 1 and 10 three-minute pitches on day 2).

 

Reproductive Epidemiology Course

Date: 2nd - 6th of September 2013, Venue: Karolinska Insitutet, Stockholm

After successfully completing this course students should be able to: - Define and explain fundamental concepts in reproductive and perinatal epidemiology such as the basic principles of reproductive physiology, demography, infectious diseases and genetics as they apply to human reproduction. - Define and explain endpoints of reproductive epidemiology such as infertility, fetal loss, birth defects, fetal growth, and maternal pregnancy complications. - Relate to scientific papers within reproductive epidemiology and compare methodological and analytical designs and epidemiological issues such as bias, errors and measures. - Discuss and reflect upon the results and conclusions of papers in reproductive epidemiology. - Being able to build own hypothesis within reproductive epidemiology.

For more information and registration please take a look at http://kiwas.ki.se/katalog/katalog/kurs/1586?lang=en 

2nd Annual Infinium HumanMethylation 450 Array Workshop

Date: 15th of April 2013, Venue: Mason Lecture Theatre, Queen Mary, University of London, Frances Bancroft Building, Mile End Road, London E1 4NS, United Kingdom

Workshop: 9:00 AM - 6:00 PM, Drinks Reception: 6:00 PM - 8:00PM

The topics covered by the meeting will be: Data analysis: recent pipelines/software EWAS Studies, EWAS study designs, and Emerging Technology: including talks from both Illumina and Partek. There are two invited speakers Kim Siegmund (Leveraging Hidden Measures to Correct for Background Fluorescence) and Christoph Bock (Analyzing and interpreting DNA methylation data).

Workshop on “Theoretical modelling, epigenetics, and trans-generational effects”

Date: 28th and 29th of November 2012, Venue: University of Southampton, UK

The workshop is aimed to on the one hand show the power of theoretical modelling for understanding and exploring the relevant concepts central in IDEAL (e.g. PAR, epigenetic regulation), and how this can serve as a guide for our experimental designs. On the other hand, the aim is to use the outcomes from our experiments and observations in (human) cohorts, as input for the models.

We very much welcome IDEAL participants to come to this workshop and contribute to discussion, and/or be there to learn and observe. Key to the success of the workshop is that the background of the participants reflects the diversity of approaches within IDEAL (thus, from people working with experimental models, theoretical modellers, and researchers of human cohorts).

 

 

Illumina 450K analysis workshop

The Infinium 450k Methylation Array Analysis Workshop was held at University College London, UK on 20 April 2012. It was a popular workshop with 120 participants from 10 EU countries. There were ten speakers including the keynote speaker, Dr Rafael Irizarry from Johns Hopkins University, USA. He discussed batch effects, probe effects and ways to avoid and deal with these problems during analysis. Other topics included validation of the 450k, a thorough comparison of available and new normalisation methods, visualisation and integration of GWAS and EWAS data and the use of the 450k to estimate copy number. There were 12 posters during the poster session and the meeting ended with a very productive discussion section followed by an evening reception at UCL's Institute of Cancer. Slides and details of the meeting can be found here:

http://www2.cancer.ucl.ac.uk/medicalgenomics/tmorris/450k.html

450k_groupphoto_edit.jpg


 

Our IDEAL

See what we’re working on at the moment!

Our IDEAL Our IDEAL

Participants

Meet the participants within IDEAL

Participants Participants

Impact on society

Check our contact with media

Impact on society Impact on society