Integrated research on Developmental determinants of Ageing and Longevity


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posted on 2014/10/09

Does evolutionary theory need a rethink?

Laland,K., Uller,T., Feldman,M., Sterelny,K., Muller,G.B., Moczek,A., Jablonka,E., Odling-Smee,J., Wray,G.A., Hoekstra,H.E., Futuyma,D.J., Lenski,R.E., Mackay,T.F., Schluter,D., Strassmann,J.E.

Nature 2014/10/09, Volume 514, Number 7521, 161-164

posted on 2014/10/01

Latent infection with cytomegalovirus is associated with poor memory CD4 responses to influenza A core proteins in the elderly

Derhovanessian,E., Maier,A.B., Hahnel,K., McElhaney,J.E., Slagboom,E.P., Pawelec,G.

J.Immunol. 2014/10/01, Volume 193, Number 7, 3624-3631

posted on 2014/10

What is an anti-aging treatment?

Exp.Gerontol. 2014/10, Volume 58, Number , 14-18

posted on 2014/09

Human longevity and variation in DNA damage response and repair: study of the contribution of sub-processes using competitive gene-set analysis

Debrabant,B., Soerensen,M., Flachsbart,F., Dato,S., Mengel-From,J., Stevnsner,T., Bohr,V.A., Kruse,T.A., Schreiber,S., Nebel,A., Christensen,K., Tan,Q., Christiansen,L.

Eur.J.Hum.Genet. 2014/09, Volume 22, Number 9, 1131-1136

posted on 2014/09

Association of adiponectin and leptin with relative telomere length in seven independent cohorts including 11,448 participants

Broer,L., Raschenberger,J., Deelen,J., Mangino,M., Codd,V., Pietilainen,K.H., Albrecht,E., Amin,N., Beekman,M., de Craen,A.J., Gieger,C., Haun,M., Henneman,P., Herder,C., Hovatta,I., Laser,A., Kedenko,L., Koenig,W., Kollerits,B., Moilanen,E., Oostra,B.A., Paulweber,B., Quaye,L., Rissanen,A., Roden,M., Surakka,I., Valdes,A.M., Vuolteenaho,K., Thorand,B., van Dijk,K.W., Kaprio,J., Spector,T.D., Slagboom,P.E., Samani,N.J., Kronenberg,F., van Duijn,C.M., Ladwig,K.H.

Eur.J.Epidemiol. 2014/09, Volume 29, Number 9, 629-638

posted on 2014/09

Meta-analysis identifies loci affecting levels of the potential osteoarthritis biomarkers sCOMP and uCTX-II with genome wide significance

Ramos,Y.F., Metrustry,S., Arden,N., Bay-Jensen,A.C., Beekman,M., de Craen,A.J., Cupples,L.A., Esko,T., Evangelou,E., Felson,D.T., Hart,D.J., Ioannidis,J.P., Karsdal,M., Kloppenburg,M., Lafeber,F., Metspalu,A., Panoutsopoulou,K., Slagboom,P.E., Spector,T.D., van Spil,E.W., Uitterlinden,A.G., Zhu,Y., Valdes,A.M., van Meurs,J.B., Meulenbelt,I.

J.Med.Genet. 2014/09, Volume 51, Number 9, 596-604

posted on 2014/09

Ecdysteroid hormones link the juvenile environment to alternative adult life histories in a seasonal insect

Oostra,V., Mateus,A.R., van der Burg,K.R., Piessens,T., van Eijk,M., Brakefield,P.M., Beldade,P., Zwaan,B.J.

Am.Nat. 2014/09, Volume 184, Number 3, E79-E92

posted on 2014/09

Decreased birth weight, length, and head circumference in children born by women years after treatment for hyperthyroidism

Ohrling,H., Torring,O., Yin,L., Iliadou,A.N., Tullgren,O., Abraham-Nordling,M., Wallin,G., Hall,P., Lonn,S.

J.Clin.Endocrinol.Metab 2014/09, Volume 99, Number 9, 3217-3223

posted on 2014/09

Birth cohort differences in the prevalence of longevity-associated variants in APOE and FOXO3A in Danish long-lived individuals

Nygaard,M., Lindahl-Jacobsen,R., Soerensen,M., Mengel-From,J., Andersen-Ranberg,K., Jeune,B., Vaupel,J.W., Tan,Q., Christiansen,L., Christensen,K.

Exp.Gerontol. 2014/09, Volume 57, Number , 41-46

posted on 2014/09

Mitochondrial DNA copy number in peripheral blood cells declines with age and is associated with general health among elderly

Mengel-From,J., Thinggaard,M., Dalgard,C., Kyvik,K.O., Christensen,K., Christiansen,L.

Hum.Genet. 2014/09, Volume 133, Number 9, 1149-1159


IDEAL dissertations

Lovisa Högberg (5th of October 2012) Prenatal influences on health outcomes over the lifespan: Effects of smoking, socio-economic status and foetal growth. Karolinska Insititute

Vicencio Oostra (26th of June 2013) Hormonal and transcriptional mechanisms underlying developmental plasticity of life histories in a seasonal butterfly. Leiden University

Oluwatosin O. Taiwo (2013) The Role of DNA Methylation in Stem Cell Ageing. University college London

Alexis Grimaldi (16th of May 2014) Crosstalk between thyroid hormones and glucocrticoids during Xenopus tropicalis metamorphosis. Le Centre national de la recherche scientifique

Joris Deelen (25th of June 2014) Genetic and biomarker studies of human longevity. Leiden University Medical Center

Marianne Nygaard (8th of July 2014) Genetic Determinants of Healthy Aging – Studies of genetic variation associated with human longevity . Southern Denmark University

Joost van de Heuvel (25th of November 2014) The evolution and plasticity of life histories upon variation in nutrition : an ageing focused integrative approach. Leiden University

Erik B. van den Akker (18th of February 2015) Computational biology in human aging. An omics data integration approach. Leiden University Medical Center

Linda Ahrenfeldt (15th of Oktober 2015) Opposite-sex vs same-sex twins: mortality, cancer and behavior. Southern Denmark University

Fenni Rusli (29th of August 2016) Diet-induced phenotypic plasticity during aging. Wageningen University.  

Book Publications

Non-Genetic Inheritance. Tobias Uller and Heikki Helanterä. Volume 1, September 2013, Pages 27-32, ISSN (Online) 2084-8846, DOI:10.2478/ng-2013-0003.

Immunosenescence: Psychosocial and Behavioral Determinants. Jos A. Bosch, Anna C. Phillips, Anna C., Janet Lord (Eds.) 2013. Gramham Pawelec and Ludmilla Müller. Introduction to Ageing of the Adaptive Immune System. Chapter 2, pp 17-32.  DOI: 10.1007/978-1-4614-4776-4_2

The Philosophy of Biology: A companion for Educators. K.Kampouakis (ed.) History, Philosophy and Theory of the Life Sciences; Volume 1, 2013. Tobias Uller. Non-Genetic Inheritance and Evolution, pp 267-287.  DOI: 10.1007/978-94-007-6537-5_14.


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