Integrated research on Developmental determinants of Ageing and Longevity

Publications

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posted on 2014/12/01

MethylAid: visual and interactive quality control of large Illumina 450k datasets

van,Iterson M., Tobi,E.W., Slieker,R.C., den Hollander,W., Luijk,R., Slagboom,P.E., Heijmans,B.T.

Bioinformatics. 2014/12/01, Volume 30, Number 23, 3435-3437

posted on 2014/12

Knee and hip articular cartilage have distinct epigenomic landscapes: implications for future cartilage regeneration approaches

den,Hollander W., Ramos,Y.F., Bos,S.D., Bomer,N., van der Breggen,R., Lakenberg,N., de Dijcker,W.J., Duijnisveld,B.J., Slagboom,P.E., Nelissen,R.G., Meulenbelt,I.

Ann.Rheum.Dis. 2014/12, Volume 73, Number 12, 2208-2212

posted on 2014/11/21

Adaptive developmental plasticity: Compartmentalized responses to environmental cues and to corresponding internal signals provide phenotypic flexibility

Mateus,A., Marques-Pita,M., Oostra,V., Lafuente,E., Brakefield,P.M., Zwaan,B.J., Beldade,P.

BMC.Biol. 2014/11/21, Volume 12, Number 1, 97

posted on 2014/11/21

Convergent evolution of complex regulatory landscapes and pleiotropy at Hox loci

Lonfat,N., Montavon,T., Darbellay,F., Gitto,S., Duboule,D.

Science 2014/11/21, Volume 346, Number 6212, 1004-1006

posted on 2014/11

Improved imputation quality of low-frequency and rare variants in European samples using the 'Genome of The Netherlands'

Deelen,P., Menelaou,A., van Leeuwen,E.M., Kanterakis,A., van Dijk,F., Medina-Gomez,C., Francioli,L.C., Hottenga,J.J., Karssen,L.C., Estrada,K., Kreiner-Moller,E., Rivadeneira,F., van Setten,J., Gutierrez-Achury,J., Westra,H.J., Franke,L., van Enckevort,D., Dijkstra,M., Byelas,H., van Duijn,C.M., de Bakker,P.I., Wijmenga,C., Swertz,M.A.

Eur.J.Hum.Genet. 2014/11, Volume 22, Number 11, 1321-1326

posted on 2014/11

Lifelong maintenance of composition, function and cellular/subcellular distribution of proteasomes in human liver

Bellavista,E., Martucci,M., Vasuri,F., Santoro,A., Mishto,M., Kloss,A., Capizzi,E., Degiovanni,A., Lanzarini,C., Remondini,D., Dazzi,A., Pellegrini,S., Cescon,M., Capri,M., Salvioli,S., D'Errico-Grigioni,A., Dahlmann,B., Grazi,G.L., Franceschi,C.

Mech.Ageing Dev. 2014/11, Volume 141-142, Number , 26-34

posted on 2014/11

Defining the role of common variation in the genomic and biological architecture of adult human height

Wood,A.R., Esko,T., Yang,J., Vedantam,S., Pers,T.H., Gustafsson,S., Chu,A.Y., Estrada,K., Luan,J., Kutalik,Z., Amin,N., Buchkovich,M.L., Croteau-Chonka,D.C., Day,F.R., Duan,Y., Fall,T., Fehrmann,R., Ferreira,T., Jackson,A.U., Karjalainen,J., Lo,K.S., Locke,A.E., Magi,R., Mihailov,E., Porcu,E., Randall,J.C., Scherag,A., Vinkhuyzen,A.A., Westra,H.J., Winkler,T.W., Workalemahu,T., Zhao,J.H., Absher,D., Albrecht,E., Anderson,D., Baron,J., Beekman,M., Demirkan,A., Ehret,G.B., Feenstra,B., Feitosa,M.F., Fischer,K., Fraser,R.M., Goel,A., Gong,J., Justice,A.E., Kanoni,S., Kleber,M.E., Kristiansson,K., Lim,U., Lotay,V., Lui,J.C., Mangino,M., Mateo,Leach,I, Medina-Gomez,C., Nalls,M.A., Nyholt,D.R., Palmer,C.D., Pasko,D., Pechlivanis,S., Prokopenko,I., Ried,J.S., Ripke,S., Shungin,D., Stancakova,A., Strawbridge,R.J., Sung,Y.J., Tanaka,T., Teumer,A., Trompet,S., van der Laan,S.W., van Setten,J., van Vliet-Ostaptchouk,J.V., Wang,Z., Yengo,L., Zhang,W., Afzal,U., Arnlov,J., Arscott,G.M., Bandinelli,S., Barrett,A., Bellis,C., Bennett,A.J., Berne,C., Bluher,M., Bolton,J.L., Bottcher,Y., Boyd,H.A., Bruinenberg,M., Buckley,B.M., Buyske,S., Caspersen,I.H., Chines,P.S., Clarke,R., Claudi-Boehm,S., Cooper,M., Daw,E.W., De Jong,P.A., Deelen,J., Delgado,G., Denny,J.C., Dhonukshe-Rutten,R., Dimitriou,M., Doney,A.S., Dorr,M., Eklund,N., Eury,E., Folkersen,L., Garcia,M.E., Geller,F., Giedraitis,V., Go,A.S., Grallert,H., Grammer,T.B., Grassler,J., Gronberg,H., de Groot,L.C., Groves,C.J., Haessler,J., Hall,P., Haller,T., Hallmans,G., Hannemann,A., Hartman,C.A., Hassinen,M., Hayward,C., Heard-Costa,N.L., Helmer,Q., Hemani,G., Henders,A.K., Hillege,H.L., Hlatky,M.A., Hoffmann,W., Hoffmann,P., Holmen,O., Houwing-Duistermaat,J.J., Illig,T., Isaacs,A., James,A.L., Jeff,J., Johansen,B., Johansson,A., Jolley,J., Juliusdottir,T., Junttila,J., Kho,A.N., Kinnunen,L., Klopp,N., Kocher,T., Kratzer,W., Lichtner,P., Lind,L., Lindstrom,J., Lobbens,S., Lorentzon,M., Lu,Y., Lyssenko,V., Magnusson,P.K., Mahajan,A., Maillard,M., McArdle,W.L., McKenzie,C.A., McLachlan,S., McLaren,P.J., Menni,C., Merger,S., Milani,L., Moayyeri,A., Monda,K.L., Morken,M.A., Muller,G., Muller-Nurasyid,M., Musk,A.W., Narisu,N., Nauck,M., Nolte,I.M., Nothen,M.M., Oozageer,L., Pilz,S., Rayner,N.W., Renstrom,F., Robertson,N.R., Rose,L.M., Roussel,R., Sanna,S., Scharnagl,H., Scholtens,S., Schumacher,F.R., Schunkert,H., Scott,R.A., Sehmi,J., Seufferlein,T., Shi,J., Silventoinen,K., Smit,J.H., Smith,A.V., Smolonska,J., Stanton,A.V., Stirrups,K., Stott,D.J., Stringham,H.M., Sundstrom,J., Swertz,M.A., Syvanen,A.C., Tayo,B.O., Thorleifsson,G., Tyrer,J.P., van Dijk,S., van Schoor,N.M., van der Velde,N., van Heemst,D., van Oort,F.V., Vermeulen,S.H., Verweij,N., Vonk,J.M., Waite,L.L., Waldenberger,M., Wennauer,R., Wilkens,L.R., Willenborg,C., Wilsgaard,T., Wojczynski,M.K., Wong,A., Wright,A.F., Zhang,Q., Arveiler,D., Bakker,S.J., Beilby,J., Bergman,R.N., Bergmann,S., Biffar,R., Blangero,J., Boomsma,D.I., Bornstein,S.R., Bovet,P., Brambilla,P., Brown,M.J., Campbell,H., Caulfield,M.J., Chakravarti,A., Collins,R., Collins,F.S., Crawford,D.C., Cupples,L.A., Danesh,J., de Faire,U., den Ruijter,H.M., Erbel,R., Erdmann,J., Eriksson,J.G., Farrall,M., Ferrannini,E., Ferrieres,J., Ford,I., Forouhi,N.G.

Nat.Genet. 2014/11, Volume 46, Number 11, 1173-1186

posted on 2014/11

The plastic fly: the effect of sustained fluctuations in adult food supply on life-history traits

van den Heuvel,J., Zandveld,J., Mulder,M., Brakefield,P.M., Kirkwood,T.B., Shanley,D.P., Zwaan,B.J.

J.Evol.Biol. 2014/11, Volume 27, Number 11, 2322-2333

posted on 2014/11

Does urinary incontinence have fetal origins? Results from a nationwide twin study

Tettamanti,G., Altman,D., Cnattingius,S., Bellocco,R., Iliadou,A.N.

Int.Urogynecol.J. 2014/11, Volume 25, Number 11, 1471-1477

posted on 2014/10/23

The 'mitoflash' probe cpYFP does not respond to superoxide

Schwarzlander,M., Wagner,S., Ermakova,Y.G., Belousov,V.V., Radi,R., Beckman,J.S., Buettner,G.R., Demaurex,N., Duchen,M.R., Forman,H.J., Fricker,M.D., Gems,D., Halestrap,A.P., Halliwell,B., Jakob,U., Johnston,I.G., Jones,N.S., Logan,D.C., Morgan,B., Muller,F.L., Nicholls,D.G., Remington,S.J., Schumacker,P.T., Winterbourn,C.C., Sweetlove,L.J., Meyer,A.J., Dick,T.P., Murphy,M.P.

Nature 2014/10/23, Volume 514, Number 7523, E12-E14

 

IDEAL dissertations

Lovisa Högberg (5th of October 2012) Prenatal influences on health outcomes over the lifespan: Effects of smoking, socio-economic status and foetal growth. Karolinska Insititute

Vicencio Oostra (26th of June 2013) Hormonal and transcriptional mechanisms underlying developmental plasticity of life histories in a seasonal butterfly. Leiden University

Oluwatosin O. Taiwo (2013) The Role of DNA Methylation in Stem Cell Ageing. University college London

Alexis Grimaldi (16th of May 2014) Crosstalk between thyroid hormones and glucocrticoids during Xenopus tropicalis metamorphosis. Le Centre national de la recherche scientifique

Joris Deelen (25th of June 2014) Genetic and biomarker studies of human longevity. Leiden University Medical Center

Marianne Nygaard (8th of July 2014) Genetic Determinants of Healthy Aging – Studies of genetic variation associated with human longevity . Southern Denmark University

Joost van de Heuvel (25th of November 2014) The evolution and plasticity of life histories upon variation in nutrition : an ageing focused integrative approach. Leiden University

Erik B. van den Akker (18th of February 2015) Computational biology in human aging. An omics data integration approach. Leiden University Medical Center

Linda Ahrenfeldt (15th of Oktober 2015) Opposite-sex vs same-sex twins: mortality, cancer and behavior. Southern Denmark University

Fenni Rusli (29th of August 2016) Diet-induced phenotypic plasticity during aging. Wageningen University.  

Book Publications

Non-Genetic Inheritance. Tobias Uller and Heikki Helanterä. Volume 1, September 2013, Pages 27-32, ISSN (Online) 2084-8846, DOI:10.2478/ng-2013-0003.

Immunosenescence: Psychosocial and Behavioral Determinants. Jos A. Bosch, Anna C. Phillips, Anna C., Janet Lord (Eds.) 2013. Gramham Pawelec and Ludmilla Müller. Introduction to Ageing of the Adaptive Immune System. Chapter 2, pp 17-32.  DOI: 10.1007/978-1-4614-4776-4_2

The Philosophy of Biology: A companion for Educators. K.Kampouakis (ed.) History, Philosophy and Theory of the Life Sciences; Volume 1, 2013. Tobias Uller. Non-Genetic Inheritance and Evolution, pp 267-287.  DOI: 10.1007/978-94-007-6537-5_14.

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