Integrated research on Developmental determinants of Ageing and Longevity

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posted on 2012/02/15

PASSion: a pattern growth algorithm-based pipeline for splice junction detection in paired-end RNA-Seq data

Zhang,Y., Lameijer,E.W., 't Hoen,P.A., Ning,Z., Slagboom,P.E., Ye,K.

Bioinformatics. 2012/02/15, Volume 28, Number 4, 479-486

posted on 2012/02/14

N-glycomic biomarkers of biological aging and longevity: A link with inflammaging

Dall'olio,F., Vanhooren,V., Chen,C.C., Slagboom,P.E., Wuhrer,M., Franceschi,C.

Ageing Res.Rev. 2012/02/14, Volume , Number , -

posted on 2012/02

Global DNA methylation levels are modulated by mitochondrial DNA variants

Bellizzi,D., D'Aquila,P., Giordano,M., Montesanto,A., Passarino,G.

Epigenomics. 2012/02, Volume 4, Number 1, 17-27

posted on 2012/01/11

Prenatal immune activation interacts with genetic Nurr1 deficiency in the development of attentional impairments

Vuillermot,S., Joodmardi,E., Perlmann,T., Ogren,S.O., Feldon,J., Meyer,U.

J.Neurosci. 2012/01/11, Volume 32, Number 2, 436-451

posted on 2012/01

Inflamm-aging of the stem cell niche: breast cancer as a paradigmatic example: breakdown of the multi-shell cytokine network fuels cancer in aged people

Bonafe,M., Storci,G., Franceschi,C.

Bioessays 2012/01, Volume 34, Number 1, 40-49

posted on 2012

Transcriptional profiling of human familial longevity indicates a role for ASF1A and IL7R

Passtoors,W.M., Boer,J.M., Goeman,J.J., van den Akker,E.B., Deelen,J., Zwaan,B.J., Scarborough,A., van der Breggen,R., Vossen,R.H., Houwing-Duistermaat,J.J., van Ommen,G.J., Westendorp,R.G., van Heemst,D., de Craen,A.J., White,A.J., Gunn,D.A., Beekman,M., Slagboom,P.E.

PLoS.One. 2012, Volume 7, Number 1, e27759

posted on 2012

Nutritional status influences peripheral immune cell phenotypes in healthy men in rural Pakistan

Alam,I., Larbi,A., Pawelec,G.

Immun.Ageing 2012, Volume 9, Number 1, 16

posted on 2012

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

Dastani,Z., Hivert,M.F., Timpson,N., Perry,J.R., Yuan,X., Scott,R.A., Henneman,P., Heid,I.M., Kizer,J.R., Lyytikainen,L.P., Fuchsberger,C., Tanaka,T., Morris,A.P., Small,K., Isaacs,A., Beekman,M., Coassin,S., Lohman,K., Qi,L., Kanoni,S., Pankow,J.S., Uh,H.W., Wu,Y., Bidulescu,A., Rasmussen-Torvik,L.J., Greenwood,C.M., Ladouceur,M., Grimsby,J., Manning,A.K., Liu,C.T., Kooner,J., Mooser,V.E., Vollenweider,P., Kapur,K.A., Chambers,J., Wareham,N.J., Langenberg,C., Frants,R., Willems-Vandijk,K., Oostra,B.A., Willems,S.M., Lamina,C., Winkler,T.W., Psaty,B.M., Tracy,R.P., Brody,J., Chen,I., Viikari,J., Kahonen,M., Pramstaller,P.P., Evans,D.M., St,Pourcain B., Sattar,N., Wood,A.R., Bandinelli,S., Carlson,O.D., Egan,J.M., Böhringer,S., van Heemst,D., Kedenko,L., Kristiansson,K., Nuotio,M.L., Loo,B.M., Harris,T., Garcia,M., Kanaya,A., Haun,M., Klopp,N., Wichmann,H.E., Deloukas,P., Katsareli,E., Couper,D.J., Duncan,B.B., Kloppenburg,M., Adair,L.S., Borja,J.B., Wilson,J.G., Musani,S., Guo,X., Johnson,T., Semple,R., Teslovich,T.M., Allison,M.A., Redline,S., Buxbaum,S.G., Mohlke,K.L., Meulenbelt,I., Ballantyne,C.M., Dedoussis,G.V., Hu,F.B., Liu,Y., Paulweber,B., Spector,T.D., Slagboom,P.E., Ferrucci,L., Jula,A., Perola,M., Raitakari,O., Florez,J.C., Salomaa,V., Eriksson,J.G., Frayling,T.M., Hicks,A.A., Lehtimaki,T., Smith,G.D., Siscovick,D.S., Kronenberg,F., van Duijn,C., Loos,R.J., Waterworth,D.M., Meigs,J.B., Dupuis,J., Richards,J.B., Voight,B.F., Scott,L.J., Steinthorsdottir,V., Dina,C., Welch,R.P., Zeggini,E., Huth,C., Aulchenko,Y.S., Thorleifsson,G., McCulloch,L.J., Ferreira,T., Grallert,H., Amin,N., Wu,G., Willer,C.J., Raychaudhuri,S., McCarroll,S.A., Hofmann,O.M., Segre,A.V., van Hoek,M., Navarro,P., Ardlie,K., Balkau,B., Benediktsson,R., Bennett,A.J., Blagieva,R., Boerwinkle,E., Bonnycastle,L.L., Bostrom,K.B., Bravenboer,B., Bumpstead,S., Burtt,N.P., Charpentier,G., Chines,P.S., Cornelis,M., Crawford,G., Doney,A.S., Elliott,K.S., Elliott,A.L., Erdos,M.R., Fox,C.S., Franklin,C.S., Ganser,M., Gieger,C., Grarup,N., Green,T., Griffin,S., Groves,C.J., Guiducci,C., Hadjadj,S., Hassanali,N., Herder,C., Isomaa,B., Jackson,A.U., Johnson,P.R., Jorgensen,T., Kao,W.H., Kong,A., Kraft,P., Kuusisto,J., Lauritzen,T., Li,M., Lieverse,A., Lindgren,C.M., Lyssenko,V., Marre,M., Meitinger,T., Midthjell,K., Morken,M.A., Narisu,N., Nilsson,P., Owen,K.R., Payne,F., Petersen,A.K., Platou,C., Proenca,C., Prokopenko,I., Rathmann,W., Rayner,N.W., Robertson,N.R., Rocheleau,G., Roden,M., Sampson,M.J., Saxena,R., Shields,B.M., Shrader,P., Sigurdsson,G., Sparso,T., Strassburger,K., Stringham,H.M., Sun,Q., Swift,A.J., Thorand,B., Tichet,J., Tuomi,T., van Dam,R.M., van Haeften,T.W., van Herpt,T., van Vliet-Ostaptchouk,J.V., Walters,G.B., Weedon,M.N., Wijmenga,C., Witteman,J., Bergman,R.N., Cauchi,S., Collins,F.S., Gloyn,A.L., Gyllensten,U., Hansen,T., Hide,W.A., Hitman,G.A., Hofman,A., Hunter,D.J., Hveem,K., Laakso,M., Morris,A.D., Palmer,C.N., Rudan,I., Sijbrands,E., Stein,L.D., Tuomilehto,J., Uitterlinden,A., Walker,M., Watanabe,R.M., Abecasis,G.R., Boehm,B.O., Campbell,H., Daly,M.J., Hattersley,A.T., Pedersen,O., Barroso,I., Groop,L., Sladek,R., Thorsteinsdottir,U., Wilson,J.F., Illig,T., Froguel,P., van Duijn,C.M., Stefansson,K., Altshuler,D., Boehnke,M., McCarthy,M.I.

PLoS.Genet. 2012, Volume 8, Number 3, e1002607-

posted on 2012

Genome-wide linkage in a highly consanguineous pedigree reveals two novel loci on chromosome 7 for non-syndromic familial Premature Ovarian Failure

Caburet,S., Zavadakova,P., Ben-Neriah,Z., Bouhali,K., Dipietromaria,A., Charon,C., Besse,C., Laissue,P., Chalifa-Caspi,V., Christin-Maitre,S., Vaiman,D., Levi,G., Veitia,R.A., Fellous,M.

PLoS.One. 2012, Volume 7, Number 3, e33412-

posted on 2011/11/24

Gene set analysis of GWAS data for human longevity highlights the relevance of the insulin/IGF-1 signaling and telomere maintenance pathways

Deelen,J., Uh,H.W., Monajemi,R., van Heemst,D., Thijssen,P.E., Böhringer,S., van den Akker,E.B., de Craen,A.J., Rivadeneira,F., Uitterlinden,A.G., Westendorp,R.G., Goeman,J.J., Slagboom,P.E., Houwing-Duistermaat,J.J., Beekman,M.

Age (Dordr.) 2011/11/24, Volume , Number , -

 

IDEAL dissertations

Lovisa Högberg (5th of October 2012) Prenatal influences on health outcomes over the lifespan: Effects of smoking, socio-economic status and foetal growth. Karolinska Insititute

Vicencio Oostra (26th of June 2013) Hormonal and transcriptional mechanisms underlying developmental plasticity of life histories in a seasonal butterfly. Leiden University

Oluwatosin O. Taiwo (2013) The Role of DNA Methylation in Stem Cell Ageing. University college London

Alexis Grimaldi (16th of May 2014) Crosstalk between thyroid hormones and glucocrticoids during Xenopus tropicalis metamorphosis. Le Centre national de la recherche scientifique

Joris Deelen (25th of June 2014) Genetic and biomarker studies of human longevity. Leiden University Medical Center

Marianne Nygaard (8th of July 2014) Genetic Determinants of Healthy Aging – Studies of genetic variation associated with human longevity . Southern Denmark University

Joost van de Heuvel (25th of November 2014) The evolution and plasticity of life histories upon variation in nutrition : an ageing focused integrative approach. Leiden University

Erik B. van den Akker (18th of February 2015) Computational biology in human aging. An omics data integration approach. Leiden University Medical Center

Linda Ahrenfeldt (15th of Oktober 2015) Opposite-sex vs same-sex twins: mortality, cancer and behavior. Southern Denmark University

Fenni Rusli (29th of August 2016) Diet-induced phenotypic plasticity during aging. Wageningen University.  

Book Publications

Non-Genetic Inheritance. Tobias Uller and Heikki Helanterä. Volume 1, September 2013, Pages 27-32, ISSN (Online) 2084-8846, DOI:10.2478/ng-2013-0003.

Immunosenescence: Psychosocial and Behavioral Determinants. Jos A. Bosch, Anna C. Phillips, Anna C., Janet Lord (Eds.) 2013. Gramham Pawelec and Ludmilla Müller. Introduction to Ageing of the Adaptive Immune System. Chapter 2, pp 17-32.  DOI: 10.1007/978-1-4614-4776-4_2

The Philosophy of Biology: A companion for Educators. K.Kampouakis (ed.) History, Philosophy and Theory of the Life Sciences; Volume 1, 2013. Tobias Uller. Non-Genetic Inheritance and Evolution, pp 267-287.  DOI: 10.1007/978-94-007-6537-5_14.

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