Integrated research on Developmental determinants of Ageing and Longevity


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posted on 2012/06

The mystery of C. elegans aging: an emerging role for fat. Distant parallels between C. elegans aging and metabolic syndrome?

Ackerman,D., Gems,D.

Bioessays 2012/06, Volume 34, Number 6, 466-471

posted on 2012/05/20

Functional T cells targeting NY-ESO-1 or Melan-A are predictive for survival of patients with distant melanoma metastasis

Weide,B., Zelba,H., Derhovanessian,E., Pflugfelder,A., Eigentler,T.K., Di Giacomo,A.M., Maio,M., Aarntzen,E.H., de Vries,I.J., Sucker,A., Schadendorf,D., Buttner,P., Garbe,C., Pawelec,G.

J.Clin.Oncol. 2012/05/20, Volume 30, Number 15, 1835-1841

posted on 2012/05/04

Transcriptome analysis of a long-lived natural Drosophila variant: a prominent role of stress- and reproduction-genes in lifespan extension

Doroszuk,A., Jonker,M.J., Pul,N., Breit,T.M., Zwaan,B.J.

BMC.Genomics 2012/05/04, Volume 13, Number 1, 167

posted on 2012/05

Prenatal famine and genetic variation are independently and additively associated with DNA methylation at regulatory loci within IGF2/H191

Tobi,E.W., Slagboom,P.E., van Dongen,J., Kremer,D., Stein,A.D., Putter,H., Heijmans,B.T., Lumey,L.H.

PLoS.One. 2012/05, Volume 7, Number 5, e37933

posted on 2012/05

Human longevity and variation in GH/IGF-1/insulin signaling, DNA damage signaling and repair and pro/antioxidant pathway genes: cross sectional and longitudinal studies

Soerensen,M., Dato,S., Tan,Q., Thinggaard,M., Kleindorp,R., Beekman,M., Jacobsen,R., Suchiman,H.E., de Craen,A.J., Westendorp,R.G., Schreiber,S., Stevnsner,T., Bohr,V.A., Slagboom,P.E., Nebel,A., Vaupel,J.W., Christensen,K., McGue,M., Christiansen,L.

Exp.Gerontol. 2012/05, Volume 47, Number 5, 379-387

posted on 2012/05

Cause-specific infant mortality in a population-based Swedish study of term and post-term births: the contribution of gestational age and birth weight

Altman,M., Edstedt Bonamy,A.K., Wikstrom,A.K., Cnattingius,S.

BMJ Open. 2012/05, Volume 2, Number 4,

posted on 2012/05

How to deal with the early GWAS data when imputing and combining different arrays is necessary

Uh,H.W., Deelen,J., Beekman,M., Helmer,Q., Rivadeneira,F., Hottenga,J.J., Boomsma,D.I., Hofman,A., Uitterlinden,A.G., Slagboom,P.E., Böhringer,S., Houwing-Duistermaat,J.J.

Eur.J.Hum.Genet. 2012/05, Volume 20, Number 5, 572-576

posted on 2012/04

Methylome analysis using MeDIP-seq with low DNA concentrations

Taiwo,O., Wilson,G.A., Morris,T., Seisenberger,S., Reik,W., Pearce,D., Beck,S., Butcher,L.M.

Nat.Protoc. 2012/04, Volume 7, Number 4, 617-636

posted on 2012/03/09

The unmet need in the elderly: How immunosenescence, CMV infection, co-morbidities and frailty are a challenge for the development of more effective influenza vaccines

McElhaney,J.E., Zhou,X., Talbot,H.K., Soethout,E., Bleackley,R.C., Granville,D.J., Pawelec,G.

Vaccine 2012/03/09, Volume 30, Number 12, 2060-2067

posted on 2012/03/05

Charting the NF-kappaB pathway interactome map

Tieri,P., Termanini,A., Bellavista,E., Salvioli,S., Capri,M., Franceschi,C.

PLoS.One. 2012/03/05, Volume 7, Number 3, e32678


IDEAL dissertations

Lovisa Högberg (5th of October 2012) Prenatal influences on health outcomes over the lifespan: Effects of smoking, socio-economic status and foetal growth. Karolinska Insititute

Vicencio Oostra (26th of June 2013) Hormonal and transcriptional mechanisms underlying developmental plasticity of life histories in a seasonal butterfly. Leiden University

Oluwatosin O. Taiwo (2013) The Role of DNA Methylation in Stem Cell Ageing. University college London

Alexis Grimaldi (16th of May 2014) Crosstalk between thyroid hormones and glucocrticoids during Xenopus tropicalis metamorphosis. Le Centre national de la recherche scientifique

Joris Deelen (25th of June 2014) Genetic and biomarker studies of human longevity. Leiden University Medical Center

Marianne Nygaard (8th of July 2014) Genetic Determinants of Healthy Aging – Studies of genetic variation associated with human longevity . Southern Denmark University

Joost van de Heuvel (25th of November 2014) The evolution and plasticity of life histories upon variation in nutrition : an ageing focused integrative approach. Leiden University

Erik B. van den Akker (18th of February 2015) Computational biology in human aging. An omics data integration approach. Leiden University Medical Center

Linda Ahrenfeldt (15th of Oktober 2015) Opposite-sex vs same-sex twins: mortality, cancer and behavior. Southern Denmark University

Fenni Rusli (29th of August 2016) Diet-induced phenotypic plasticity during aging. Wageningen University.  

Book Publications

Non-Genetic Inheritance. Tobias Uller and Heikki Helanterä. Volume 1, September 2013, Pages 27-32, ISSN (Online) 2084-8846, DOI:10.2478/ng-2013-0003.

Immunosenescence: Psychosocial and Behavioral Determinants. Jos A. Bosch, Anna C. Phillips, Anna C., Janet Lord (Eds.) 2013. Gramham Pawelec and Ludmilla Müller. Introduction to Ageing of the Adaptive Immune System. Chapter 2, pp 17-32.  DOI: 10.1007/978-1-4614-4776-4_2

The Philosophy of Biology: A companion for Educators. K.Kampouakis (ed.) History, Philosophy and Theory of the Life Sciences; Volume 1, 2013. Tobias Uller. Non-Genetic Inheritance and Evolution, pp 267-287.  DOI: 10.1007/978-94-007-6537-5_14.


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