Integrated research on Developmental determinants of Ageing and Longevity

Publications

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posted on 2014

Temporal dynamics and developmental memory of 3D chromatin architecture at Hox gene loci

Noordermeer,D., Leleu,M., Schorderet,P., Joye,E., Chabaud,F., Duboule,D.

Elife. 2014, Volume 3, Number , e02557-

posted on 2013/12/18

Genes Of Human Longevity: An Endless Quest?

Capri,M., Santoro,A., Garagnani,P., Bacalini,M.G., Pirazzini,C., Olivieri,F., Procopio,A., Salvioli,S., Franceschi,C.

Curr.Vasc.Pharmacol. 2013/12/18, Volume , Number , -

posted on 2013/12/17

The co-occurrence of mtDNA mutations on different oxidative phosphorylation subunits, not detected by haplogroup analysis, affects human longevity and is population specific

Raule,N., Sevini,F., Li,S., Barbieri,A., Tallaro,F., Lomartire,L., Vianello,D., Montesanto,A., Moilanen,J.S., Bezrukov,V., Blanche,H., Hervonen,A., Christensen,K., Deiana,L., Gonos,E.S., Kirkwood,T.B., Kristensen,P., Leon,A., Pelicci,P.G., Poulain,M., Rea,I.M., Remacle,J., Robine,J.M., Schreiber,S., Sikora,E., Eline,Slagboom P., Spazzafumo,L., Antonietta,Stazi M., Toussaint,O., Vaupel,J.W., Rose,G., Majamaa,K., Perola,M., Johnson,T.E., Bolund,L., Yang,H., Passarino,G., Franceschi,C.

Aging Cell 2013/12/17, Volume , Number , -

posted on 2013/12/10

Assessment of osteoarthritis candidate genes in a meta-analysis of 9 genome-wide association studies

Rodriguez-Fontenla,C., Calaza,M., Evangelou,E., Valdes,A.M., Arden,N., Blanco,F.J., Carr,A., Chapman,K., Deloukas,P., Doherty,M., Esko,T., Garces,C.M., Gomez-Reino,J.J., Helgadottir,H., Hofman,A., Jonsdottir,I., Kerkhof,H.J., Kloppenburg,M., McCaskie,A., Ntzani,E.E., Ollier,W.E., Oreiro,N., Panoutsopoulou,K., Ralston,S.H., Ramos,Y.F., Riancho,J.A., Rivadeneira,F., Slagboom,P.E., Styrkarsdottir,U., Thorsteinsdottir,U., Thorleifsson,G., Tsezou,A., Uitterlinden,A.G., Wallis,G.A., Wilkinson,J.M., Zhai,G., Zhu,Y., Felson,D.T., Ioannidis,J.P., Loughlin,J., Metspalu,A., Meulenbelt,I., Stefansson,K., van Meurs,J.B., Zeggini,E., Spector,T.D., Gonzalez,A.

Arthritis Rheum. 2013/12/10, Volume , Number , -

posted on 2013/12/04

Breast cancer risk in opposite-sexed twins: influence of birth weight and co-twin birth weight

Hajiebrahimi,M., Bahmanyar,S., Oberg,S., Iliadou,A.N., Cnattingius,S.

J.Natl.Cancer Inst. 2013/12/04, Volume 105, Number 23, 1833-1836

posted on 2013/12

Aging as accelerated accumulation of somatic variants: whole-genome sequencing of centenarian and middle-aged monozygotic twin pairs

Ye,K., Beekman,M., Lameijer,E.W., Zhang,Y., Moed,M.H., van den Akker,E.B., Deelen,J., Houwing-Duistermaat,J.J., Kremer,D., Anvar,S.Y., Laros,J.F., Jones,D., Raine,K., Blackburne,B., Potluri,S., Long,Q., Guryev,V., van der Breggen,R., Westendorp,R.G., 't Hoen,P.A., den Dunnen,J., van Ommen,G.J., Willemsen,G., Pitts,S.J., Cox,D.R., Ning,Z., Boomsma,D.I., Slagboom,P.E.

Twin.Res.Hum.Genet. 2013/12, Volume 16, Number 6, 1026-1032

posted on 2013/12

The control region of mitochondrial DNA shows an unusual CpG and non-CpG methylation pattern

Bellizzi,D., D'Aquila,P., Scafone,T., Giordano,M., Riso,V., Riccio,A., Passarino,G.

DNA Res. 2013/12, Volume 20, Number 6, 537-547

posted on 2013/12

Functional metagenomic profiling of intestinal microbiome in extreme ageing

Rampelli,S., Candela,M., Turroni,S., Biagi,E., Collino,S., Franceschi,C., O'Toole,P.W., Brigidi,P.

Aging (Albany.NY) 2013/12, Volume 5, Number 12, 902-912

posted on 2013/12

Birth weight and adult bone metabolism are unrelated: results from birth weight-discordant monozygotic twins

Frost,M., Petersen,I., Andersen,T.L., Langdahl,B.L., Buhl,T., Christiansen,L., Brixen,K., Christensen,K.

J.Bone Miner.Res. 2013/12, Volume 28, Number 12, 2561-2569

posted on 2013/11/01

Value of biomarkers in osteoarthritis: current status and perspectives

Lotz,M., Martel-Pelletier,J., Christiansen,C., Brandi,M.L., Bruyere,O., Chapurlat,R., Collette,J., Cooper,C., Giacovelli,G., Kanis,J.A., Karsdal,M.A., Kraus,V., Lems,W.F., Meulenbelt,I., Pelletier,J.P., Raynauld,J.P., Reiter-Niesert,S., Rizzoli,R., Sandell,L.J., Van Spil,W.E., Reginster,J.Y.

Ann.Rheum.Dis. 2013/11/01, Volume 72, Number 11, 1756-1763

 

IDEAL dissertations

Lovisa Högberg (5th of October 2012) Prenatal influences on health outcomes over the lifespan: Effects of smoking, socio-economic status and foetal growth. Karolinska Insititute

Vicencio Oostra (26th of June 2013) Hormonal and transcriptional mechanisms underlying developmental plasticity of life histories in a seasonal butterfly. Leiden University

Oluwatosin O. Taiwo (2013) The Role of DNA Methylation in Stem Cell Ageing. University college London

Alexis Grimaldi (16th of May 2014) Crosstalk between thyroid hormones and glucocrticoids during Xenopus tropicalis metamorphosis. Le Centre national de la recherche scientifique

Joris Deelen (25th of June 2014) Genetic and biomarker studies of human longevity. Leiden University Medical Center

Marianne Nygaard (8th of July 2014) Genetic Determinants of Healthy Aging – Studies of genetic variation associated with human longevity . Southern Denmark University

Joost van de Heuvel (25th of November 2014) The evolution and plasticity of life histories upon variation in nutrition : an ageing focused integrative approach. Leiden University

Erik B. van den Akker (18th of February 2015) Computational biology in human aging. An omics data integration approach. Leiden University Medical Center

Linda Ahrenfeldt (15th of Oktober 2015) Opposite-sex vs same-sex twins: mortality, cancer and behavior. Southern Denmark University

Fenni Rusli (29th of August 2016) Diet-induced phenotypic plasticity during aging. Wageningen University.  

Book Publications

Non-Genetic Inheritance. Tobias Uller and Heikki Helanterä. Volume 1, September 2013, Pages 27-32, ISSN (Online) 2084-8846, DOI:10.2478/ng-2013-0003.

Immunosenescence: Psychosocial and Behavioral Determinants. Jos A. Bosch, Anna C. Phillips, Anna C., Janet Lord (Eds.) 2013. Gramham Pawelec and Ludmilla Müller. Introduction to Ageing of the Adaptive Immune System. Chapter 2, pp 17-32.  DOI: 10.1007/978-1-4614-4776-4_2

The Philosophy of Biology: A companion for Educators. K.Kampouakis (ed.) History, Philosophy and Theory of the Life Sciences; Volume 1, 2013. Tobias Uller. Non-Genetic Inheritance and Evolution, pp 267-287.  DOI: 10.1007/978-94-007-6537-5_14.

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