Integrated research on Developmental determinants of Ageing and Longevity


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posted on 2014/01

Serum profiling of healthy aging identifies phospho- and sphingolipid species as markers of human longevity

Montoliu,I., Scherer,M., Beguelin,F., Dasilva,L., Mari,D., Salvioli,S., Martin,F.P., Capri,M., Bucci,L., Ostan,R., Garagnani,P., Monti,D., Biagi,E., Brigidi,P., Kussmann,M., Rezzi,S., Franceschi,C., Collino,S.

Aging (Albany.NY) 2014/01, Volume 6, Number 1, 9-25

posted on 2014/01

Conservation and divergence of regulatory strategies at Hox Loci and the origin of tetrapod digits

Woltering,J.M., Noordermeer,D., Leleu,M., Duboule,D.

PLoS.Biol. 2014/01, Volume 12, Number 1, e1001773-

posted on 2014

Age-related changes of adaptive and neuropsychological features in persons with Down Syndrome

Ghezzo,A., Salvioli,S., Solimando,M.C., Palmieri,A., Chiostergi,C., Scurti,M., Lomartire,L., Bedetti,F., Cocchi,G., Follo,D., Pipitone,E., Rovatti,P., Zamberletti,J., Gomiero,T., Castellani,G., Franceschi,C.

PLoS.One. 2014, Volume 9, Number 11, e113111-

posted on 2014

The three genetics (nuclear DNA, mitochondrial DNA, and gut microbiome) of longevity in humans considered as metaorganisms

Garagnani,P., Pirazzini,C., Giuliani,C., Candela,M., Brigidi,P., Sevini,F., Luiselli,D., Bacalini,M.G., Salvioli,S., Capri,M., Monti,D., Mari,D., Collino,S., Delledonne,M., Descombes,P., Franceschi,C.

Biomed.Res.Int. 2014, Volume 2014, Number , 560340-

posted on 2014

Gut microbiome in Down syndrome

Biagi,E., Candela,M., Centanni,M., Consolandi,C., Rampelli,S., Turroni,S., Severgnini,M., Peano,C., Ghezzo,A., Scurti,M., Salvioli,S., Franceschi,C., Brigidi,P.

PLoS.One. 2014, Volume 9, Number 11, e112023-

posted on 2014

Considerations when investigating lncRNA function in vivo

Bassett,A.R., Akhtar,A., Barlow,D.P., Bird,A.P., Brockdorff,N., Duboule,D., Ephrussi,A., Ferguson-Smith,A.C., Gingeras,T.R., Haerty,W., Higgs,D.R., Miska,E.A., Ponting,C.P.

Elife. 2014, Volume 3, Number , e03058-

posted on 2014

The nucleolar size is associated to the methylation status of ribosomal DNA in breast carcinomas

Bacalini,M.G., Pacilli,A., Giuliani,C., Penzo,M., Trere,D., Pirazzini,C., Salvioli,S., Franceschi,C., Montanaro,L., Garagnani,P.

BMC.Cancer 2014, Volume 14, Number , 361-

posted on 2014

DNA methylation signatures link prenatal famine exposure to growth and metabolism

Tobi,E.W., Goeman,J.J., Monajemi,R., Gu,H., Putter,H., Zhang,Y., Slieker,R.C., Stok,A.P., Thijssen,P.E., Muller,F., van Zwet,E.W., Bock,C., Meissner,A., Lumey,L.H., Eline,Slagboom P., Heijmans,B.T.

Nat.Commun. 2014, Volume 5, Number , 5592-

posted on 2014

Epigenetic signature of birth weight discordance in adult twins

Tan,Q., Frost,M., Heijmans,B.T., von Bornemann,Hjelmborg J., Tobi,E.W., Christensen,K., Christiansen,L.

BMC.Genomics 2014, Volume 15, Number , 1062-

posted on 2014

Genes involved in the osteoarthritis process identified through genome wide expression analysis in articular cartilage; the RAAK study

Ramos,Y.F., den Hollander,W., Bovee,J.V., Bomer,N., van der Breggen,R., Lakenberg,N., Keurentjes,J.C., Goeman,J.J., Slagboom,P.E., Nelissen,R.G., Bos,S.D., Meulenbelt,I.

PLoS.One. 2014, Volume 9, Number 7, e103056-


IDEAL dissertations

Lovisa Högberg (5th of October 2012) Prenatal influences on health outcomes over the lifespan: Effects of smoking, socio-economic status and foetal growth. Karolinska Insititute

Vicencio Oostra (26th of June 2013) Hormonal and transcriptional mechanisms underlying developmental plasticity of life histories in a seasonal butterfly. Leiden University

Oluwatosin O. Taiwo (2013) The Role of DNA Methylation in Stem Cell Ageing. University college London

Alexis Grimaldi (16th of May 2014) Crosstalk between thyroid hormones and glucocrticoids during Xenopus tropicalis metamorphosis. Le Centre national de la recherche scientifique

Joris Deelen (25th of June 2014) Genetic and biomarker studies of human longevity. Leiden University Medical Center

Marianne Nygaard (8th of July 2014) Genetic Determinants of Healthy Aging – Studies of genetic variation associated with human longevity . Southern Denmark University

Joost van de Heuvel (25th of November 2014) The evolution and plasticity of life histories upon variation in nutrition : an ageing focused integrative approach. Leiden University

Erik B. van den Akker (18th of February 2015) Computational biology in human aging. An omics data integration approach. Leiden University Medical Center

Linda Ahrenfeldt (15th of Oktober 2015) Opposite-sex vs same-sex twins: mortality, cancer and behavior. Southern Denmark University

Fenni Rusli (29th of August 2016) Diet-induced phenotypic plasticity during aging. Wageningen University.  

Book Publications

Non-Genetic Inheritance. Tobias Uller and Heikki Helanterä. Volume 1, September 2013, Pages 27-32, ISSN (Online) 2084-8846, DOI:10.2478/ng-2013-0003.

Immunosenescence: Psychosocial and Behavioral Determinants. Jos A. Bosch, Anna C. Phillips, Anna C., Janet Lord (Eds.) 2013. Gramham Pawelec and Ludmilla Müller. Introduction to Ageing of the Adaptive Immune System. Chapter 2, pp 17-32.  DOI: 10.1007/978-1-4614-4776-4_2

The Philosophy of Biology: A companion for Educators. K.Kampouakis (ed.) History, Philosophy and Theory of the Life Sciences; Volume 1, 2013. Tobias Uller. Non-Genetic Inheritance and Evolution, pp 267-287.  DOI: 10.1007/978-94-007-6537-5_14.


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