Integrated research on Developmental determinants of Ageing and Longevity


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posted on 2014/02/01

ChAMP: 450k Chip Analysis Methylation Pipeline

Morris,T.J., Butcher,L.M., Feber,A., Teschendorff,A.E., Chakravarthy,A.R., Wojdacz,T.K., Beck,S.

Bioinformatics. 2014/02/01, Volume 30, Number 3, 428-430

posted on 2014/02/01

Relationship between the functional exon 3 deleted growth hormone receptor polymorphism and symptomatic osteoarthritis in women

Claessen,K.M., Kloppenburg,M., Kroon,H.M., Bijsterbosch,J., Pereira,A.M., Romijn,J.A., van der Straaten,T., Nelissen,R.G., Hofman,A., Uitterlinden,A.G., Duijnisveld,B.J., Lakenberg,N., Beekman,M., van Meurs,J.B., Slagboom,P.E., Biermasz,N.R., Meulenbelt,I.

Ann.Rheum.Dis. 2014/02/01, Volume 73, Number 2, 433-436

posted on 2014/02

Evolution of sexually dimorphic longevity in humans

Aging (Albany.NY) 2014/02, Volume 6, Number 2, 84-91

posted on 2014/02

The Genome of the Netherlands: design, and project goals

Boomsma,D.I., Wijmenga,C., Slagboom,E.P., Swertz,M.A., Karssen,L.C., Abdellaoui,A., Ye,K., Guryev,V., Vermaat,M., van Dijk,F., Francioli,L.C., Hottenga,J.J., Laros,J.F., Li,Q., Li,Y., Cao,H., Chen,R., Du,Y., Li,N., Cao,S., van Setten,J., Menelaou,A., Pulit,S.L., Hehir-Kwa,J.Y., Beekman,M., Elbers,C.C., Byelas,H., de Craen,A.J., Deelen,P., Dijkstra,M., den Dunnen,J.T., de Knijff,P., Houwing-Duistermaat,J., Koval,V., Estrada,K., Hofman,A., Kanterakis,A., Enckevort,Dv, Mai,H., Kattenberg,M., van Leeuwen,E.M., Neerincx,P.B., Oostra,B., Rivadeneira,F., Suchiman,E.H., Uitterlinden,A.G., Willemsen,G., Wolffenbuttel,B.H., Wang,J., de Bakker,P.I., van Ommen,G.J., van Duijn,C.M.

Eur.J.Hum.Genet. 2014/02, Volume 22, Number 2, 221-227

posted on 2014/02

DAF-16/FoxO Directly Regulates an Atypical AMP-Activated Protein Kinase Gamma Isoform to Mediate the Effects of Insulin/IGF-1 Signaling on Aging in Caenorhabditis elegans

Tullet,J.M., Araiz,C., Sanders,M.J., Au,C., Benedetto,A., Papatheodorou,I., Clark,E., Schmeisser,K., Jones,D., Schuster,E.F., Thornton,J.M., Gems,D.

PLoS.Genet. 2014/02, Volume 10, Number 2, e1004109-

posted on 2014/02

Rudimentary signs of immunosenescence in Cytomegalovirus-seropositive healthy young adults

Turner,J.E., Campbell,J.P., Edwards,K.M., Howarth,L.J., Pawelec,G., Aldred,S., Moss,P., Drayson,M.T., Burns,V.E., Bosch,J.A.

Age (Dordr.) 2014/02, Volume 36, Number 1, 287-297

posted on 2014/02

MDL-1, a growth- and tumor-suppressor, slows aging and prevents germline hyperplasia and hypertrophy in C. elegans

Riesen,M., Feyst,I., Rattanavirotkul,N., Ezcurra,M., Tullet,J.M., Papatheodorou,I., Ziehm,M., Au,C., Gilliat,A.F., Hellberg,J., Thornton,J.M., Gems,D.

Aging (Albany.NY) 2014/02, Volume 6, Number 2, 98-117

posted on 2014/01/14

Leukocyte telomere length associates with prospective mortality independent of immune-related parameters and known genetic markers

Deelen,J., Beekman,M., Codd,V., Trompet,S., Broer,L., Hagg,S., Fischer,K., Thijssen,P.E., Suchiman,H.E., Postmus,I., Uitterlinden,A.G., Hofman,A., de Craen,A.J., Metspalu,A., Pedersen,N.L., van Duijn,C.M., Wouter,Jukema J., Houwing-Duistermaat,J.J., Samani,N.J., Eline,Slagboom P.

Int.J.Epidemiol. 2014/01/14, Volume , Number , -

posted on 2014/01/06

The neurodegenerative effects of selenium are inhibited by FOXO and PINK1/PTEN regulation of insulin/insulin-like growth factor signaling in Caenorhabditis elegans

Estevez,A.O., Morgan,K.L., Szewczyk,N.J., Gems,D., Estevez,M.

Neurotoxicology 2014/01/06, Volume 41C, Number , 28-43

posted on 2014/01/02

Present and future of anti-ageing epigenetic diets

Bacalini,M.G., Friso,S., Olivieri,F., Pirazzini,C., Giuliani,C., Capri,M., Santoro,A., Franceschi,C., Garagnani,P.

Mech.Ageing Dev. 2014/01/02, Volume , Number , -


IDEAL dissertations

Lovisa Högberg (5th of October 2012) Prenatal influences on health outcomes over the lifespan: Effects of smoking, socio-economic status and foetal growth. Karolinska Insititute

Vicencio Oostra (26th of June 2013) Hormonal and transcriptional mechanisms underlying developmental plasticity of life histories in a seasonal butterfly. Leiden University

Oluwatosin O. Taiwo (2013) The Role of DNA Methylation in Stem Cell Ageing. University college London

Alexis Grimaldi (16th of May 2014) Crosstalk between thyroid hormones and glucocrticoids during Xenopus tropicalis metamorphosis. Le Centre national de la recherche scientifique

Joris Deelen (25th of June 2014) Genetic and biomarker studies of human longevity. Leiden University Medical Center

Marianne Nygaard (8th of July 2014) Genetic Determinants of Healthy Aging – Studies of genetic variation associated with human longevity . Southern Denmark University

Joost van de Heuvel (25th of November 2014) The evolution and plasticity of life histories upon variation in nutrition : an ageing focused integrative approach. Leiden University

Erik B. van den Akker (18th of February 2015) Computational biology in human aging. An omics data integration approach. Leiden University Medical Center

Linda Ahrenfeldt (15th of Oktober 2015) Opposite-sex vs same-sex twins: mortality, cancer and behavior. Southern Denmark University

Fenni Rusli (29th of August 2016) Diet-induced phenotypic plasticity during aging. Wageningen University.  

Book Publications

Non-Genetic Inheritance. Tobias Uller and Heikki Helanterä. Volume 1, September 2013, Pages 27-32, ISSN (Online) 2084-8846, DOI:10.2478/ng-2013-0003.

Immunosenescence: Psychosocial and Behavioral Determinants. Jos A. Bosch, Anna C. Phillips, Anna C., Janet Lord (Eds.) 2013. Gramham Pawelec and Ludmilla Müller. Introduction to Ageing of the Adaptive Immune System. Chapter 2, pp 17-32.  DOI: 10.1007/978-1-4614-4776-4_2

The Philosophy of Biology: A companion for Educators. K.Kampouakis (ed.) History, Philosophy and Theory of the Life Sciences; Volume 1, 2013. Tobias Uller. Non-Genetic Inheritance and Evolution, pp 267-287.  DOI: 10.1007/978-94-007-6537-5_14.


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