Integrated research on Developmental determinants of Ageing and Longevity


Kick off meeting Dutch Society for Research on Ageing

April 15, 2016, Leiden, The Netherlands

Scheltema, Marktsteeg 1, 2312 CS Leiden

In 2015, the Dutch Society for Research on Ageing (DuSRA, or in Dutch: NVVVO) was founded by representatives of the Leiden University Medical Center, Erasmus University Medical Centre, Wageningen University & Research Centre and the University Medical Center Groningen. This Society aims to stimulate the ageing field to link basic and translational science by bringing clinical, biomedical and basic scientists together.

  1. We like to invite you to the Kick off meeting of the DuSRA on April 15, 2016 in Leiden. Please find the programme attached (below). If you intend to come, please bring a poster so that colleagues in the field, industry and funding bodies present at the meeting, learn about your work.
  2. For many years international peers have rated Ageing Research in The Netherlands as excellent. In January 2016 an international expert panel discussed the ageing research agenda and the conclusions of this Lorentz meeting will be presented at the DuSRA kick-off. Keynote speaker in the afternoon is Professor L. Ferrucci, scientific director of the National Institute of Ageing (NIA) who will indicate how the NIA is moving from basic to translational science in ageing. We have selected a program of Dutch scientists that will give insights into the excellence in ageing research at various biological levels. There is ample time for discussing the translational ageing research agenda, and we value input from all stakeholders. Your presence and contribution to these discussions is crucial.
  3. To become a member (costs 50 euro per year) of the society please follow the link to fill in the application form and in addition for attending the meeting please send mail to:

Have a look on the program for more information of this meeting.


Translational aging research: challenges and opportunities

Lorentz meeting 

January 6-8, 2016, Leiden, The Netherlands

Aim. The Lorentz workshop brought clinicians, epidemiologists, basic scientists and computational scientists together to focus on the translational potential of knowledge created in the field of ageing research. Although it became clear that research in elderly people to improve care, biomedical research to improve the health span, and basic science to unravel molecular and cellular ageing mechanisms are different scientific communities the aim of the meeting was to find innovative ways to improve communication and to seek common research questions. Moreover, we aimed to describe how the instruments and tools in model systems can be placed at the service of Population and Patient-based studies to deliver true translational research: the end result should be applicable in the clinic, in prevention, diagnosis or treatment.

The Lorentz meeting advised on five major points of improvement to stimulate translational research:

             i.     Improving communication and joint programs for basic and clinical sciences.

            ii.     Improving the understanding and modulation of human ageing.

           iii.     Improving research in the human biomedical and medical domain.

           iv.     Improving accessibility of human big data and biological material.

            v.     Support for future focus.

For more information:


Connecting Development and Late Life Health

Epigenetic mechanisms and beyond

October 12-14, 2015, Leiden, The Netherlands

The IDEAL consortium organizes a conference to disseminate the results. The aim of the conference is to integrate the expertise of medical health care professionals and basic researchers in the field of development, childhood behavior, adult health and ageing. Attendants will learn about a range of early life exposures leading to childhood, adult or late life consequences and clinical problems. The current evidence that early life exposures cause late life consequences will be evaluated in the light of theories such as the Barker hypothesis. Furthermore it will be discussed how this early-late life link may be explained through the most up to date knowledge of genome biology and epigenetic regulation. Ideally, these discussions result in consensus of suitable study designs to investigate the early-late life links and in notion how the current knowledge may contribute to an understanding of and solutions for the clinical problems encountered.

leiden stadsgehoorzaal

Fourth Annual Meeting 2015 in Bologna!

The fourth annual meeting of the IDEAL consortium has taken place from February Wednesday 25 till Friday 27, 2015 in Bologna at the the Department of Experimental, Diagnostic and Specialty Medicine, University of Bologna, via S. Giacomo 12.

ideal group bologna


Nils Bömer wins the IDEAL young investigators grant of €10.000 EUR

dsc 0495 v2The IDEAL management team initiated a contest for the best research proposal written by IDEAL young investigators. During the 3rd annual IDEAL meeting at Friday 28th of February three young investigators had the opportunity to present their proposal to the audience and the scientific advisory board, who were asked to rate the proposals. The winner of the young investigators competition 2014 was Nils Bömer with his proposal “Dietary intake is an important mechanism mediating OA susceptibility of the ageing cartilage”. He will use the €10.000 for the generation of gene expression data in the knee cartilage of mice at T=6, 12, 24 and 28 month, with and without a nutritional invention to assess the nutritional influences on the homeostasis of aging cartilage.



Steve Horvath as invited keynote speaker at the 2014 IDEAL Annual Meeting

The IDEAL young investigators committee had invited prof dr Steve Horvath for a keynote lecture on the Epigenetic clock. Steve Horvath is professor Human Genetics and Biostatistics at the University of California, Los Angeles and he gave a very interesting lecture about the DNA methylation age of different tissues and the potential association with health.

 stevehorvath ideal2014

Third Annual Meeting 2014 'Epigenetic Setpoint & Biomarkers'

ideal group leiden 2014The third annual meeting of the IDEAL consortium has taken  place from February 26 till February 28, 2014 in Leiden at the Leiden University Medical Center. The scientific part of the annual meeting for IDEAL was entitled 'Epigenetic Setpoints & Biomarkers' and focussed on the achievements within these major IDEAL themes.

The atmosphere of the meeting was very pleasant and the meeting was very succesfull in bringing research groups closer together.



Second Annual Meeting 2013 'Connectivity'

The second annual meeting of the IDEAL consortium took place from February 28 till March 2, 2013 in Paris at the Museum National d’Histoire Naturelle. The scientific part of the annual meeting for IDEAL was entitled 'Connectivity' and focussed on the opportunities for collaboration. The IDEAL consortium meeting was inspiring and plans for connecting developmental research with longevity research have been made.

annual meeting 2013 foto klein



The Wednesday before the IDEAL annual meeting, 27th of February 2013, the IDEAL 450K DNA methylation workshop was scheduled. The first topic was 'Pre-processing 450k data' where normalisation methods and new Chip Analysis Methylation Pipeline have been discussed. The second topic was 'Design, sampling, analysis, annotation, and interpretation in 450k studies' where studies have been discussed in which association with methylation differences have been identified within identical twins discordant for birth weight, within different tissues, with ageing and Down Syndrome.


First Annual Meeting 2012kasteel oud poelgeest

The first annual meeting of the IDEAL consortium was organized from March 1-3, 2012. The event was hosted by the Leiden University Medical Center and took place at Castle "Oud Poelgeest"

During the meeting around 65 researchers were present. In an open and pleasant atmosphere they presented their work progress of the past year and discussed the planning for the next year.

IDEAL is a very broad project with a lot of different points of view and research lines. To ensure a good integration of all research perspectives working along thematic lines will be further intensified the coming year.


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